Research Topics
Work is in progress in the following areas:
1. Biofabrication and Tissue-Mimetic Systems
We advance next-generation biofabrication techniques to create complex, physiologically relevant tissue models. Using tools such as volumetric 3D printing, coaxial extrusion, and curvature-guided design, we develop vascularized constructs that mimic the geometry, flow dynamics, and mechanical behavior of native tissues. These platforms enable high-fidelity models for tumor biology, vascular disease, and regenerative medicine.
Key themes:
- Volumetric and extrusion-based bioprinting
- Geometry-driven mechanobiology
- Perfusable vascular networks and tumor-stroma models
- Small-diameter vessel engineering
- High-throughput soft tissue modeling
2. Engineered Living Materials and Microbial Biofabrication
We explore microbial systems as functional components of materials, using bacteria and biopolymers to create living, adaptive scaffolds. Our work includes bacteria-mediated mineralization, bacterial cellulose-based architectures, and oxygen-guided morphogenesis. These systems are integrated into bone tissue platforms, bioactive coatings, and 4D shape-morphing materials, enabling a new class of engineered living constructs.
Key themes:
- Engineered living materials (ELMs)
- Bacterial cellulose structuring
- Oxygen-releasing particles for microbial patterning
- Self-assembling and shape-evolving scaffolds
- Hybrid biological-inorganic materials for regeneration
3. Sustainable Biointerfaces and Circular Biomanufacturing through Chemical and Biochemical Engineering
We apply principles of biochemical and chemical engineering to transform biological waste streams into valuable functional materials. By integrating enzyme-mimetic nanomaterials, stimuli-responsive platforms, and AI-driven bioprocess optimization, we develop scalable solutions for both biomedical and industrial applications. Our work includes hydrothermal co-liquefaction of food and fish waste, biopolymer extraction from insect residues, and green synthesis of antioxidant nanozymes, supporting the transition toward a circular bioeconomy.
Key themes:
- Biochemical and chemical engineering for waste valorization
- Stimuli-responsive and antioxidant nanozymes
- ROS modulation and regenerative therapies
- Hydrothermal liquefaction for biocrude and material recovery
- AI/ML-assisted bioprocess design and fermentation optimization